Endocrine Abstracts

Introduction: Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency is the most common of the CAH, it is also the most common of the autosomal recessive diseases. Hypertension is generally absent, and its presence should lead to an investigation of another cause.Observation: We report the case of a 26-year-old young man, descendant from a second-degree consanguineous marriage with a family history of the death of a brother at the age of 2...

Introduction: Pseudohypoparathyroidism (PHP) is a part of a very rare heterogeneous group of endocrine disorders. It is caused by alterations in the PTH receptor, which is encoded by the GNAS1 gene inducing target tissue resistance to PTH. Pseudohypoparathyroidism typically gets discovered during early childhood, rare are the cases discovered in adulthood.Observation: Herein the case of a 35-year-old man, descendant of a non-consanguineous marriage, with...

Introduction: Diabetes distress (DD) refers to the emotional burdens and worries, often hidden, that are part of the spectrum of the patient experience when managing a chronic and demanding disease like diabetes. The objective of this work was to determine the prevalence of DD and its clinical determinants in type 2 diabetic patients.Patients and methods: Cross-sectional study conducted on 92 type 2 diabetic patients who consulted on an outpatient basis ...

Introduction: The coexistence of Grave disease [GD] and Myasthenia gravis [MG] may present a diagnostic dilemma especially concerning ocular manifestations. 3–10% of myasthenic patients exhibit GD, while MG is reported in only <1% of patients with thyroid disorder.Observation:Case 1: A 32-year-old woman, with a medical history of vitiligo, was diagnosed with GD. Immunology revealed positive anti-thyroid peroxidase antibod...

IntroductionPheochromocytomas are rare catecholamine-producing neuroendocrine tumors derived from the sympathetic or parasympathetic nervous system. The clinical presentation of pheocromocytoma has varying forms, which makes diagnosing it challenging. Here, we report a case of Adrenergic cardiomyopathy mimicking COVID-19.Case reportA 40-year-old woman with a history of pulmonary edema during cesarean delivery...

IntroductionThe atypical parathyroid adenoma is a histological diagnosis. It is a parathyroid tumor with atypical histological features different from an adenoma and not similar enough to be considered as a carcinoma.It has an uncertain malignant potential.ObservationWe report the case of a 55 year-old woman, referred to us by her rhumatologist after discovering a severe hypercalcemia when exploring her for o...

IntroductionPheochromocytoma is rare neuroendocrine tumor arising from the chromaffin cells of the adrenal medulla. It can be even sporadic or take part of inherited syndromes.ObservationWe report the case of a young 32 year-old woman followed by her oncologist for medullary thyroid cancer treated with surgery and radiotherapy. On the examination of the removed tissue, there was a bilateral cancer, measuring ...

Introduction: Diabetes stigma (DS) refers to the experience of negative feelings such as exclusion, blame, rejection, or judgment due to having a chronic disease. The objective of this work was to measure the DS and its clinical determinants in type 2 diabetic patients.Patients and methods: Cross-sectional study conducted on 84 type 2 diabetic patients who consulted on an outpatient basis between September and December 2021. DS was assessed using the ara...

IntroductionVon Hippel-Lindau (VHL) syndrome is an autosomal dominant disease resulting in a susceptibility to develop central nervous system and retinal hemangioblastomas, endolymphatic sac tumors, renal clear cell carcinoma and pheochromocytoma. Pheochromocytoma occurs usually at a younger age and tends to be bilateral in VHL syndrome. Herein, we describe a case of VHL syndrome with cerebellar hemangioblastoma, bilateral pheochromocytoma and kidney tum...

IntroductionThe adrenocortical carcinoma(ACC) is a rare malignant tumor arising from the adrenal cortex, it is usually associated to abnormal hormone secretion, but sometimes it is nonfunctioning, leading to a delayed diagnosis with a locally advanced and/or a metastatic disease. ObservationWe report the case of a 42 year-old woman with no medical history who consulted for chronic epigastralgia. On physical e...